吡咯喹啉醌
排泄
刺激
生物化学
化学
细菌
孵化
微生物
生物
内分泌学
酶
辅因子
遗传学
作者
M Ameyama,Kyoko Matsushita,Emiko Shinagawa,Michitoshi Hayashi,Osao Adachi
出处
期刊:Biofactors
[Wiley]
日期:1988-01-01
卷期号:1 (1): 51-3
被引量:8
摘要
A marked excretion of pyrroloquinoline quinone (PQQ) by methylotrophs into the culture medium was observed when incubation was prolonged to the late stationary phase. When the organisms were growing vigorously in the early exponential phase, accumulation of PQQ was repressed at a low level. Some evidence was obtained that the excretion of PQQ is related to turnover of quinoproteins of the organisms. The growth stimulation of microorganisms by PQQ was demonstrated using Acetobacter aceti. The presence of PQQ even at the pg/ml level in the culture medium stimulated the bacterial growth by reducing the lag time. The growth stimulating effect of PQQ was observed only by the reduction of the lag time but not by increase in either the subsequent growth rate or the total cell yield. The results indicated that PQQ must have an important role in the initiation of cell reproduction.
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