[Research progress of animal model of allergic rhinitis].

The animal model of allergic rhinitis is ciritical for the study of this disease.Guinea pig,mouse,rat,rabbit and other animals can be selected.Allergen includes ovalbumin,pollen,dust mites,available fungi,roundworm and schistosome antigen.Aluminum hydroxide adjuvant is most commonly used.To enhance the sensitivity,nasal drops can be selected,inhalation and multi-point subcutaneous injection is optional.Nasal itching,sneezing,clear nasal discharge ,or specific histopathological and immunological results can indicate the success of modeling.Immunological test is the most important standard to determine whether the model is successful or not.This review summarizes the recent advances in the study of animal models of allergic rhinitis.