Synthesis of novel β-functionalized α-oximinoketones via hetero-Michael addition of alcohols and mercaptans to enones

A new methodology has been developed for the preparation of β-alkoxy and β-sulfenyl ketones by hetero-Michael addition of the corresponding alcohols and thiols to enones under acidic and basic conditions. The direct conversion of enones into β-alkoxy and β-sulfenyl α-oximinoketones was also described.