医学
多导睡眠图
持续气道正压
艾普沃思嗜睡量表
阻塞性睡眠呼吸暂停
麻醉
睡眠呼吸暂停
气道正压
肺功能测试
心脏病学
中枢性睡眠呼吸暂停
呼吸暂停
亚临床感染
内科学
作者
Tarek A. Dernaika,Maroun M. Tawk,Shoab A. Nazir,Walid G. Younis,Gary T. Kinasewitz
出处
期刊:Chest
[Elsevier]
日期:2007-07-01
卷期号:132 (1): 81-87
被引量:120
标识
DOI:10.1378/chest.06-2562
摘要
To determine whether central sleep apnea (CSA) occurring during continuous positive airway pressure (CPAP) titration in patients with obstructive sleep apnea (OSA) reflects subclinical congestive heart failure (CHF), and whether these events will improve with CPAP therapy.Cross-sectional analysis of patients with suspected sleep-related breathing disorders referred for split-night polysomnographyForty-two OSA patients with and without CPAP-related CSA were analyzed. All CSA patients (n = 21) and control subjects (n = 21) underwent echocardiography, pulmonary function testing, and arterial blood gas (ABG) analysis. Repeat polysomnography with CPAP was performed 2 to 3 months after adequate CPAP therapy in CSA group patients.Demographic, Epworth sleepiness scale, pulmonary function test, ABG, and baseline diagnostic polysomnography findings were similar in both groups. There was no difference in the prevalence of subclinical left ventricular systolic dysfunction in the CSA group vs the control group. CSA patients had decreased sleep efficiency (SE), increased sleep stage 1 percentage, sleep stages shift, wake time after sleep onset (WASO), and total arousals compared to control subjects. Twelve of 14 patients (92%) in the CSA group demonstrated complete or near-complete resolution of CSA events on follow-up polysomnography and showed improvement in SE, WASO, and total arousals compared to their baseline study.CSA events occurring during CPAP titration are transient and self-limited. They may be precipitated by the sleep fragmentation associated with initial CPAP titration and are not associated with an increased prevalence of occult CHF compared to OSA patients without CPAP-related CSA.
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