S‐Trifluoroethyl Benzenesulfonothioate: A Bench‐Stable Reagent for Electrophilic Trifluoroethylthiolation†

Summary of main observation and conclusion We report herein a practical approach for synthesis of an electrophilic trifluoroethylthiolation reagent PhSO 2 SCH 2 CF 3 ( 1 ) from easily available materials. The reaction proceeded through a protonation and nucleophilic substitution cascade of the in situ formed trifluorodiazoethane. This bench‐stable reagent could easily be applied to introduce trifluoroethylthio group into small organic molecules.