Hypoxia and Cardiac Function in Patients With Prior Myocardial Infarction

HomeCirculation ResearchVol. 132, No. 9Hypoxia and Cardiac Function in Patients With Prior Myocardial Infarction No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextHypoxia and Cardiac Function in Patients With Prior Myocardial Infarction Jan-Niklas Hönemann, Darius Gerlach, Fabian Hoffmann, Tilmann Kramer, Henning Weis, Christine E. Hellweg, Bikash Konda, Vlad G. Zaha, Hesham A. Sadek, Antonius E. van Herwarden, André J. Olthaar, Hannes Reuter, Stephan Baldus, Benjamin D. Levine, Jens Jordan, Jens Tank and Ulrich Limper Jan-Niklas HönemannJan-Niklas Hönemann https://orcid.org/0000-0001-6261-1446 Department of Internal Medicine III, Division of Cardiology, Pneumology, Angiology, and Intensive Care (J.-N.H., F.H., T.K., S.B.), University of Cologne, Germany. German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). *J.-N. Hönemann, D. Gerlach, J. Tank, and U. Limper contributed equally. Search for more papers by this author , Darius GerlachDarius Gerlach https://orcid.org/0000-0001-7044-6065 German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). *J.-N. Hönemann, D. Gerlach, J. Tank, and U. Limper contributed equally. Search for more papers by this author , Fabian HoffmannFabian Hoffmann https://orcid.org/0000-0002-3199-9924 Department of Internal Medicine III, Division of Cardiology, Pneumology, Angiology, and Intensive Care (J.-N.H., F.H., T.K., S.B.), University of Cologne, Germany. German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Search for more papers by this author , Tilmann KramerTilmann Kramer https://orcid.org/0000-0003-0265-7607 Department of Internal Medicine III, Division of Cardiology, Pneumology, Angiology, and Intensive Care (J.-N.H., F.H., T.K., S.B.), University of Cologne, Germany. German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Search for more papers by this author , Henning WeisHenning Weis https://orcid.org/0000-0001-8638-3281 Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne (H.W.), University of Cologne, Germany. German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Search for more papers by this author , Christine E. HellwegChristine E. Hellweg https://orcid.org/0000-0002-2223-3580 German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Search for more papers by this author , Bikash KondaBikash Konda German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Search for more papers by this author , Vlad G. ZahaVlad G. Zaha https://orcid.org/0000-0003-4878-891X Division of Cardiology, Department of Internal Medicine (V.G.Z., H.A.S., B.D.L.), UT Southwestern Medical Center, Dallas, TX. Advanced Imaging Research Center (V.G.Z.), UT Southwestern Medical Center, Dallas, TX. Search for more papers by this author , Hesham A. SadekHesham A. Sadek https://orcid.org/0000-0002-4745-366X Division of Cardiology, Department of Internal Medicine (V.G.Z., H.A.S., B.D.L.), UT Southwestern Medical Center, Dallas, TX. Center for Regenerative Science and Medicine (H.A.S.), UT Southwestern Medical Center, Dallas, TX. Search for more papers by this author , Antonius E. van HerwardenAntonius E. van Herwarden Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (A.E.v.H., A.J.O.). Search for more papers by this author , André J. OlthaarAndré J. Olthaar Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (A.E.v.H., A.J.O.). Search for more papers by this author , Hannes ReuterHannes Reuter Cardiology Department, EVK Weyertal, Cologne, Germany (H.R.). Search for more papers by this author , Stephan BaldusStephan Baldus https://orcid.org/0000-0001-8259-1737 Department of Internal Medicine III, Division of Cardiology, Pneumology, Angiology, and Intensive Care (J.-N.H., F.H., T.K., S.B.), University of Cologne, Germany. Search for more papers by this author , Benjamin D. LevineBenjamin D. Levine https://orcid.org/0000-0001-9064-7251 Division of Cardiology, Department of Internal Medicine (V.G.Z., H.A.S., B.D.L.), UT Southwestern Medical Center, Dallas, TX. Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, Dallas (B.D.L.). Search for more papers by this author , Jens JordanJens Jordan https://orcid.org/0000-0003-4518-0706 German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Head of Aerospace Medicine, University of Cologne, Germany (J.J.). Search for more papers by this author , Jens TankJens Tank Correspondence to: Jens Tank, MD, Institute of Aerospace Medicine, Linder Hoehe, 51147 Cologne, Germany. Email E-mail Address: [email protected] https://orcid.org/0000-0002-5672-1187 German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). *J.-N. Hönemann, D. Gerlach, J. Tank, and U. Limper contributed equally. Search for more papers by this author and Ulrich LimperUlrich Limper https://orcid.org/0000-0001-9927-4180 German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany (J.-N.H., D.G., F.H., T.K., H.W., C.E.H., B.K., J.J., J.T., U.L.). Department of Anesthesiology and Intensive Care Medicine, Merheim Medical Center, Hospitals of Cologne, University of Witten/Herdecke, Germany (U.L.). *J.-N. Hönemann, D. Gerlach, J. Tank, and U. Limper contributed equally. Search for more papers by this author Originally published3 Apr 2023https://doi.org/10.1161/CIRCRESAHA.122.322334Circulation Research. 2023;132:1165–1167is related toMeet the First AuthorsFootnotes*J.-N. Hönemann, D. Gerlach, J. Tank, and U. Limper contributed equally.For Sources of Funding and Disclosures, see page 1167.Correspondence to: Jens Tank, MD, Institute of Aerospace Medicine, Linder Hoehe, 51147 Cologne, Germany. Email jens.[email protected]deReferences1. Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, et al. Hypoxia induces heart regeneration in adult mice.Nature. 2017; 541:222–227. doi: 10.1038/nature20173CrossrefMedlineGoogle Scholar2. Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM. Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody.Radiat Res. 2002; 158:486–492. doi: 10.1667/0033-7587(2002)158[0486:qdoiid]2.0.co;2CrossrefMedlineGoogle Scholar3. Uecker M, Zhang S, Frahm J. Nonlinear inverse reconstruction for real-time MRI of the human heart using undersampled radial FLASH.Magn Reson Med. 2010; 63:1456–1462. doi: 10.1002/mrm.22453CrossrefMedlineGoogle Scholar4. Hoffmann F, Limper U, Zaha VG, Reuter H, Zange L, Schulz-Menger J, Hein M, Baldus S, Levine BD, Jordan J, et al. Evolution of pulmonary hypertension during severe sustained hypoxia.Circulation. 2020; 141:1504–1506. doi: 10.1161/CIRCULATIONAHA.119.045192LinkGoogle Scholar5. Wu L, Sowers JR, Zhang Y, Ren J. Targeting DNA damage response in cardiovascular diseases: from pathophysiology to therapeutic implications.Cardiovasc Res. 2022:cvac080. doi: 10.1093/cvr/cvac080CrossrefMedlineGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesMeet the First AuthorsCirculation Research. 2023;132:1102-1103 April 28, 2023Vol 132, Issue 9 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.122.322334PMID: 37009742 Originally publishedApril 3, 2023 Keywordshypoxiatranslational sciencealtitudeheart failuremyocardial infarctionbiomedicalPDF download Advertisement SubjectsChronic Ischemic Heart Disease