纳米医学
忧虑
魔术(望远镜)
毒性
纳米技术
癌症
医学
心理学
材料科学
物理
纳米颗粒
内科学
天文
认知心理学
作者
Mahfoozur Rahman,Javed Ahmad,Imran Kazmi,Sohail Akhter,Muhammad Afzal,Gaurav Gupta,Vivek Ranjan Sinha
出处
期刊:Current Drug Discovery Technologies
[Bentham Science]
日期:2012-10-02
卷期号:9 (4): 319-329
被引量:62
标识
DOI:10.2174/157016312803305898
摘要
Multi drug resistance and non specific targeting is a major problem with conventional therapy. To overcome this problem, nanoparticles (NPs) have emerged as an important tool to deliver conventional drugs, recombinant proteins, vaccines and more recently, nucleotides. NPs modify the drug release pattern, absorption, distribution, metabolism, excretion (ADME) and therapeutic response. This review focuses on the potential of nanotechnology in cancer and discusses the different nanoparticulate drug-delivery systems including quantum dot, iron oxide nanoparticles, gold nanoparticles, carbon nanotubes, silica nanoparticles, dendrimer, graphene and polymeric nanoparticles with their applications in therapeutics, diagnostics, and imaging pattern. Further, the recent development and progress of theranostic nanoparticles in the treatment of cancer and toxicity associated with nanoparticles is also covered here.
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