Reversible Insertion of Aldehydes and Ketones into CH Bonds of Chiral Bis(oxazoline)/Iridium Complexes

BOX of tricks: Facile, reversible, and diastereoselective functionalizations of methylene CH bonds with carbonyl compounds have been observed within chiral bis(oxazoline)/iridium complexes (see structure; O red, N blue, P orange, Ir purple). These reactions are described and discussed together with the classic CH oxidative additions to iridium that occur within these same compounds.