Kang Shuai Lao Pian exerts anti-aging effects by enhancing mitochondrial oxidative metabolism

Our work highlights that KSLP promotes mitochondrial rejuvenation in aged mice by coordinately enhancing pyruvate oxidation capacity and electron transport chain (ETC) efficiency. Furthermore, we reveal the molecular landscapes by which KSLP regulates aging in diverse organs, offering a promising strategy for maintaining mitochondrial oxidative metabolism and delaying aging.