The application of nanomaterials in drug delivery system

Drug delivery system (DDS) is a key technology platform for optimizing the distribution of drugs in the body. It improves the the efficiency of drug treatment and reduces side effects by regulating the dose, time and target location. This review focuses on the application progress of nanomaterials in DDS. Liposomes, albumin nanoparticles and magnetic iron oxide nanoparticles are widely used due to their good biocompatibility, targeted drug release ability and imaging application potential. However, these materials also have certain limitations. Liposomes have low drug loading capacity, and their product Doxil shows low tolerance and certain adverse reactions. New nanomaterials are being developed and tried to be used in DDS. Innovative materials such as nano gels and metal organic frameworks (MOFs) have the capacity of reprinting a large number of drugs and low toxicity and application potential. These materials are in the research stage and are expected to play a significant role in future clinical applications.