医学
氟达拉滨
苯达莫司汀
环磷酰胺
细胞因子释放综合征
布仑妥昔单抗维多汀
CD30
淋巴瘤
胃肠病学
内科学
肿瘤科
外科
化疗
嵌合抗原受体
癌症
免疫疗法
美罗华
作者
Carlos A. Ramos,Natalie S. Grover,Anne Beaven,Premal Lulla,Meng-Fen Wu,Anastasia Ivanova,Tao Wang,Thomas C. Shea,Cliona M. Rooney,Christopher Dittus,Steven I. Park,Adrian P. Gee,Paul W. Eldridge,Kathryn McKay,Birju Mehta,Catherine Cheng,Faith Brianne Buchanan,Bambi Grilley,Kaitlin Morrison,Malcolm K. Brenner
摘要
Chimeric antigen receptor (CAR) T-cell therapy of B-cell malignancies has proved to be effective. We show how the same approach of CAR T cells specific for CD30 (CD30.CAR-Ts) can be used to treat Hodgkin lymphoma (HL).
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