Adverse effects of 131I therapy for differentiated thyroid cancer

DTC is considered the most common endocrine neoplasm, and 131I therapy has been proven to be an important component in the management strategy. Currently, most research focuses on the adverse effects of radiation exposure to 131I therapy. Some results, based on large-scale and long-term inves- tigation, show new information. Although 131I therapies are usually well tolerated, clinicians involved in the management of DTC need to be aware of the potential toxicity of 131I and take all measures to reduce these effects to a minimum. The aim of this review is to present the adverse effects of 131I therapy for DTC. Key words: Thyroid neoplasms ;  Radiotherapy;  Iodine radioisotopes ;  Adverse effects