医学
椎间盘
遗传增强
疾病
生物信息学
干细胞
间充质干细胞
变性(医学)
临床试验
病理
基因
外科
细胞生物学
生物
遗传学
腰椎
作者
Daniel R. Fassett,Mark F. Kurd,Alexander R. Vaccaro
出处
期刊:Journal of Spinal Disorders & Techniques
[Lippincott Williams & Wilkins]
日期:2009-05-29
卷期号:22 (4): 297-308
被引量:42
标识
DOI:10.1097/bsd.0b013e31816d5f64
摘要
Biologic therapies for intervertebral disk regeneration have produced very encouraging results in both in vitro and in vivo studies. Despite successful experimental results, these therapies face a number of hurdles before acceptance for human use including safety concerns, efficacy in high-order animal and human studies, and issues with the role and timing of these treatments.
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