斑秃
头皮
皮肤病科
绒毛
毛囊
医学
脱发
疤痕性秃发
背景(考古学)
鉴别诊断
毛发病
病理
生物
内科学
古生物学
作者
Eleni Ieremia,Catherine M. Stefanato
标识
DOI:10.1016/j.humpath.2023.03.015
摘要
The histopathological assessment of scalp biopsies for the diagnosis of alopecia is most commonly undertaken in specialist centers. Occasionally, pathologists encounter such specimens outside a specialist setting or at a low frequency, which makes a confident diagnosis difficult. A methodical approach is essential to identify and interpret the histopathological findings, and one of the diagnostic tools is the use of follicular counts and ratios. This method is particularly emphasized in the context of non-scarring alopecia and, furthermore, for the identification of alopecias with overlapping features. We raised the question as to what is the role of follicular hair counts and ratios in the differential diagnosis of non-scarring alopecia with overlapping features, and sought the answer in our literature review. The English literature on the histopathological assessment of horizontal scalp biopsies taken for the evaluation of non-scarring alopecia, focusing on hair follicle counting as a diagnostic tool, with particular emphasis on androgenetic alopecia, alopecia areata, and telogen effluvium, was reviewed. Follicular counts and ratios are a helpful diagnostic tool. However, these need to be coupled with the morphological features specific for each alopecia subtype to render a confident diagnosis.
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