Radiomic model for preoperative prediction of mismatch repair deficiency in gastric cancer: a multicenter study integrating tumor sub-region radiomics and transcriptomics

Gastric cancer (GC) remains a major global health challenge, because of its poor prognosis and limited treatment options in advanced stages[1][1],[2][2]. Recent advancements in immunotherapy, highlighted by the findings of the CHECKMATE-649, ORIENT-16, and KEYNOTE-859 trials, have markedly