重氮
化学
胺气处理
效力
组合化学
2-吡啶酮
抗菌活性
分子
偶氮偶合
体外
有机化学
细菌
生物化学
生物
遗传学
作者
Vinod Kumar,J. Keshavayya,Mallikarjuna Niluvanji Matada,Sudhanva M. Srinivasa,Shobith Rangappa
标识
DOI:10.1002/slct.201904954
摘要
Abstract A series of heterocyclic disperse azo dyes having pyridone architecture was prepared by a simple, economical and highly efficient diazo‐coupling method. In this method, butyl pyridone was used as a common coupling component by changing the five heterocyclic amine moieties. The structural investigations of the analogous compounds were accomplished by various spectroscopic techniques. Further, all the azo dyes were examined for their potency towards antibacterial, antituberculosis and anticancer activities. The results revealed that all the dye molecules exhibited excellent tuberculosis activity and also very promising anticancer activity. In the case of the antibacterial assay, only a few azo dyes displayed good inhibition effect towards the tested bacterial strains.
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