These studies have demonstrated that the bone bonding ability of a titanium alloy material could be evaluated by testing the titanium alloy material in a simulated body fluid (SBF). The capability of forming hydroxyapatite on the surface of a titanium alloy material in SBF has been considered to indicate its bone bonding potential. To the extent that titanium alloy may be capable of inducing hydroxyapatite formation in a SBF, any surface modification can lead to enhanced osseointegration. It was the purpose of this study, as the phase of our program addressing the subject of bone bonding titanium alloy implant, to investigate the potential of titanium for inducing hydroxyapatite formation in a simulated body fluid.