PROCEEDING IN THE CONFIGURATION OF DIPEPTIDE SWEETENER

Dipeptide sweeteners are strict in the N-terminal ,but many changes could be well tolerated in the C-terminal amino acid of the dipeptide.In order to further investigest the model of dipeptide sweetener,this thesis analysed some aspartame derivatives.The study confirmed that the size in X is not critical for the sweetness potency,but the peptide bond and the hydrogen of amide in the peptide bond is essential for sweetness.