Heterogeneous geminal-atom catalysis: Cross-coupling reactions through the pair single-atom sites

Heterogeneous single-atom catalysts (SACs) have the potential to revolutionize organic synthesis. Recently, in Nature, Lu and co-workers developed geminal-atom catalysts (GACs) for catalyzing complex molecular cross-coupling reactions. In this reaction, the cooperativity of metal centers in the geminal sites enabled the efficient activation of substrates through a dynamic bridge-coupling mechanism. Heterogeneous single-atom catalysts (SACs) have the potential to revolutionize organic synthesis. Recently, in Nature, Lu and co-workers developed geminal-atom catalysts (GACs) for catalyzing complex molecular cross-coupling reactions. In this reaction, the cooperativity of metal centers in the geminal sites enabled the efficient activation of substrates through a dynamic bridge-coupling mechanism.