The therapeutic potential of pomegranate in the prevention and management of noncommunicable diseases

studies, and clinical trials. Recent investigations have identified key bioactive constituents, including punicalagin, ellagic acid, gallic acid, and urolithin A, as major contributors to these therapeutic effects. This review provides an overview of the metabolomic profile of pomegranate, its therapeutic potential, safety, and quality control assessments, and strategies to enhance the stability and bioavailability of its active constituents, thus underscoring its potential as a natural intervention for the prevention and treatment of NCDs.