Posterior parietal cortex oscillatory activity reflects persistent spatial memory impairments induced by early hippocampal amyloidosis in male mice

induces alterations in spatial and habituation memory, associated with PPC aberrant oscillatory activity, several days after hippocampal synaptic plasticity and network activity disturbances were found. We provide an electrophysiological PPC-mediated substrate for persistent spatial memory deficits and the temporal progression pattern of the early oscillatory deleterious effects caused by Aβ.