Objective To compare the value of the Postpartum Depression Screening Scale(PDSS)and the Edinburgh Postnatal Depression scale(EPDS)in the screening of postpartum depression.Methods A total of 378 women within 42 days postpartum completed PDSS,the Edinburgh Postnatal Depression Scale(EPDS)and Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition(SCID-I/P).The SCID-I/P was regarded the standard for postpartum depression diagnosis.Results The cut-of score for PDSS and EPDS was 76 and 13,respectively.Sensitivity of PDSS was 92.00%,and specificity was 95.25%,with positive predictive value of 77.02% and negative predictive value of 99.01%.Sensitivity of EPDS was 82.30%,and specificity was 81.33%,with positive predictive value of 44.73% and negative predictive value of 97.30%.The sensitivity,specificity and positive predictive value showed significantly difference between PDSS and EPDS(P0.05),and negative predictive value had no statistical significant differece.Conclusion PDSS scale is more suitable for screening postpartum depression than EPDS scale.