Efficacy of Eculizumab in Coexisting Complement C3 Glomerulopathy and Atypical Hemolytic Uremic Syndrome

Complement-mediated kidney diseases are a currently evolving area in nephrology. Two kidney diseases associated with dysregulation of the complement alternative pathway are atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G, including C3 glomerulonephritis and dense deposit disease [DDD]).1