This paper optimizes the process of tellurium extraction through alkaline leaching with orthogonal method,investigates the influence of leaching temperature,NaOH concentration,liquid-solid ratio and leaching time on leaching efficiency of Te and meanwhile studies leaching of main impurity elements Si,Se and Cu under the optimal leaching process.The result shows that leaching temperature,NaOH concentration,liquid-solid ratio and leaching time do not have significant influence on leaching efficiency of Te.The optimal leaching process of tellurium extraction through alkaline leaching is: leaching temperature 95℃,NaOH concentration 3 moL/L,liquid-solid ratio 6∶1 and leaching time 3 h.The leaching agent under such process conditions has a high content of Si and Se.It is necessary to eliminate impurities before conducting subsequent Te extraction processes.