Genotypic Characterization of Thalassemia in Huadu District, Guangzhou, China: A Single-Center Retrospective Study

(18%). The mutation profile in Huadu District aligns with the Southern Chinese thalassemia spectrum but exhibits regional specificity, mirroring the overall epidemiological pattern of Southern China while demonstrating distinct regional mutation clusters. Greater emphasis should be placed on thalassemia screening, genetic counseling, and prenatal diagnosis to improve birth outcomes.