颂歌
重叠感染
生物
基本再生数
季节性
拉伤
应用数学
流行病模型
马尔可夫链
数学
传输(电信)
统计
病毒学
计算机科学
生态学
人口学
人口
病毒
社会学
解剖
电信
作者
Kaniz Fatema Nipa,Sophia R.‐J. Jang,Linda J. S. Allen
标识
DOI:10.1142/s0218339023500419
摘要
The effects of seasonality on disease invasion and superinfection are investigated in dengue epidemic models with two viral strains. A two-strain host–vector nonautonomous ODE is formulated with seasonal periodicity in either vector recruitment or transmission. The basic reproduction number is derived and the dynamics of the single-strain periodic subsystem are summarized. Conditions for uniform persistence and existence of a single-strain periodic solution are verified and the invasion reproduction number is derived. A time-nonhomogeneous, continuous-time Markov chain (CTMC) is formulated from the ODE framework. The basic and invasion reproduction numbers apply to the ODE and CTMC. In the case of invasion, after one strain is established and the invasion reproduction number exceeds one, the ODE predicts a successful invasion, but in the CTMC, there is a periodic probability of invasion that depends on time and size of the invasion. A multitype branching process approximation of the CTMC provides an analytical method to predict the periodic probability of invasion. The numerical results show that the peak time of invasion is related to the current endemic strain and the dominant seasonal driver but it often precedes the peak time of the seasonal driver.
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