CDCP1-targeting ADC outperforms standard therapies in Ras-mutant pancreatic cancer

-mutant pancreatic cancers, outperforming gemcitabine and FOLFIRINOX and achieving complete tumor remission for up to 100 days-even following relapse after standard chemotherapy. These findings support the potential of 2G10-PNU159682 as a promising therapeutic candidate for the treatment of Ras-mutant cancers.