Extrapancreatic Autoimmunity in Patients With Latent Autoimmune Diabetes of Adults

Type 1 diabetes often occurs in association with other autoimmune diseases (thyroid disease [1–3], Addison’s disease [2], celiac disease [1,3], autoimmune gastropathy [4], and others), with autoimmune thyroiditis beingthe most common (1–3). To determine whether these autoimmune diseases are also more frequent in patients with latent autoimmune diabetes of adults (LADA), we compared the prevalence of anti–21 α-hydroxylase (21OHAb), anti–thyroid peroxidase (TPOAb), anti–parietal gastric cell antibodies, and rheumatoid factor in a group of patients with LADA versus patients with type 2 diabetes. Fifty-four patients with LADA (>35 years of age at diagnosis who did not require insulin for …