卤化物
镍
电解
催化作用
芳基
阳极
电化学
组合化学
化学
产量(工程)
有机化学
无机化学
材料科学
冶金
电极
物理化学
电解质
烷基
作者
Dong Liu,Zhao‐Ran Liu,Cong Ma,Ke‐Jin Jiao,Bing Sun,Lei Wei,Julien Lefranc,Simon Herbert,Tian‐Sheng Mei
标识
DOI:10.1002/anie.202016310
摘要
Abstract A novel strategy for the N‐arylation of NH‐sulfoximines has been developed by merging nickel catalysis and electrochemistry (in an undivided cell), thereby providing a practical method for the construction of sulfoximine derivatives. Paired electrolysis is employed in this protocol, so a sacrificial anode is not required. Owing to the mild reaction conditions, excellent functional group tolerance and yield are achieved. A preliminary mechanistic study indicates that the anodic oxidation of a Ni II species is crucial to promote the reductive elimination of a C−N bond from the resulting Ni III species at room temperature.
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