This study investigated the relationship between infants` temperament and mothers` parenting stress. This investigation is done by focusing on the interaction effects between the infants` temperament and maternal factors. A total of 1,120 infants and their mothers from a national sample were selected as suejects for carrying this investigation. The EAS (Emotionality, Activity and Sociality) Temperament Survey for Children: Parental Ratings was used to measure the infants` emotionality temperament, and PSI-SF(Parenting Stress Index-Short Form), KMSS(Kansas Marital Satisfaction Scale) and a survey on socio-demographic variables were used for the maternal factors. Two-way ANOVA revealed that the parenting stress was significantly different according to the infants`emotionality temperament. Most importantly, there were significant interaction effects between the infants` emotionality temperament and maternal factors(education level, employment status and marital satisfaction). The results were discussed in terms of the goodness of fit of the temperament and parenting models.