In this paper, squid paste as organic cadmium additive and CdCl2 as inorganic cadmium additive were used to study the accumulation of different forms of cadmium and toxicity in shrimp. The results indicate that cadmium mainly accumulate in the purtenance of shrimp, which did not vary significantly with organic cadmium and inorganic cadmium. The concentration of cadmium in shrimp correlates well with both culture time and cadmium concentration in feedstuff. However, shrimps fed with inorganic cadmium addtive have a higher tissue content than those fed with organic cadmium addtive during the same culture time. Mortality in shrimp of the organic cadmium group is higher than the inorganic cadmium group.All the test data were analyzed for food safety and sanitation.