Objective To investigate the relationship between pulmonary hemorrhage and pneumothorax in patients undergoing lung biopsy.Materials and Methods CT guided lung biopsy was performed in 168 patients using 18 Gauge semi-automatic slot cutting biopsy needle.Results Pneumothorax was found in 63 cases(37.5%) after lung biopsy,and pulmonary hemorrhage was seen in 76 cases(45.2%).Pulmonary hemorrhage negatively associated with the presence of pneumothorax(P0.01).Incidence of pneumothorax decreased in patients with pulmonary hemorrhage after lung biopsy(P0.05).Conclusion Pulmonary hemorrhage around the biopsy site might decrease the risk of pneumothorax in patients undergoing lung biopsy.