Regulation of chitinase genes expression in bacteria

Chitinases, which can hydrolyze chitin, occur in a wide range of microorganisms including viruses, bacteria, and fungi.The derivatives of chitin are potentially useful in several areas such as food processing, medicines, and biological control in agriculture.Some bacteria can uptake and utilize chitin as carbon source by secreting chitinase.The chitin is degraded into chito-oligosaccharides [(GlcNAc) n ] or N-acetylglucosamine (GlcNAc) by chitinases, and then the chitin derivatives are transferred into cells by specific transport systems of bacteria.The intracellular chitin derivatives activate or suppress the transcription of a series of chi genes and affect the amount of chitinase.The expression of chitinase genes are strictly regulated by various regulatory factors and responsive cis-acting elements.The present review will focus on the transport system and the regulation of chitinase genes expression in bacteria.