Monitoring the Process of Tissue Healing of Mouse Skin in vivo after Laser Irradiation Based on Optical Coherence Tomography

Er:YAG laser(2 940 nm,2.5 J/cm2,single spot, 4 times) was irradiation on a mouse skin in vivo,and the skin which before irradiation and the process of renovating scathe that irradiated after Er:YAG laser were observed by an optical coherence tomography(OCT).The results indicate that the optical parameters of post-laser irradiation tissue have changed distinctly.The reasons concerning some complications were analyzed by the optical parameters' changes and the major factors of the complications in laser skin rejuvenation were expected to be found.