对映选择合成
化学
轴对称性
砜
催化作用
组合化学
离子交换
有机化学
离子
结构工程
工程类
作者
Peng-Fei Lian,Ying Wang,Duo Li,Shu‐Yu Zhang,Abing Duan,He‐Yuan Bai,He‐Yuan Bai
标识
DOI:10.1021/acs.orglett.4c00704
摘要
A novel ion exchange strategy has been developed to enable the asymmetric construction of axially chiral sulfone-containing styrenes. This approach provides a practical synthesis pathway for various axially chiral sulfone-containing styrenes with good yields, exceptional enantioselectivities, and nearly complete E/Z selectivities. Additionally, the reaction mechanism is elucidated in detail through density functional theory (DFT) calculations.
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