The significance of m6A-circFOXK2 in CD4+T cells from patients with rheumatoid arthritis and circFOXK2 correlates with Th17 % and autophagy

We indicated a notable decrease in the m6A-methylated level of circFOXK2 in CD4⁺T cells from human RA, indicating a potential role of hypomethylated circFOXK2 in CD4⁺T cells function and RA pathogenesis. This may show valuable insight into the ALKBH5/m6A-circFOXK2/miRNA interaction network and the mechanism of RA.