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Very first experience with 68Ga/177Lu-NYM096 in patients with metastatic clear cell renal cell carcinoma
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Pubmed搜不到,doi没找到,文章期刊为Journal of Nuclear Medicine, https://jnm.snmjournals.org/content/66/supplement_1/251260
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| DOI |
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| 其它 |
Wenjia Zhu, Li Huo, Meixi Liu, Xinchun Yan, Xiaoyuan Li, Guoyang Zheng and Yushi Zhang Journal of Nuclear Medicine June 2025, 66 (supplement 1) 251260; Introduction: NYM096 is a new-generation carbonic anhydrase 9 (CA9) targeting small molecule that can be labeled with both 68Ga and 177Lu. It has a higher affinity (almost 100-fold) for CA9 compared to NYM005. In this study, we aim to evaluate the safety, tolerability, and imaging characteristics of 68Ga-NYM096 and the safety, dosimetry, and recommended phase 2 dose of 177Lu-NYM096 in patients with metastatic clear cell renal cell carcinoma (ccRCC). |
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(2025-6-4)