Gas–Liquid Microchemical Oxidation for Continuous Synthesis Processes: A Short Review

Abstract Gas–liquid oxidation processes, despite their wide application in the chemical industry, still pose considerable safety concerns. Microchemical technology has received high recognition for its intrinsic safety performance and process-intensification capability in hazardous reactions. This Short Review offers a comprehensive summary on how microchemical technology can be employed to achieve gas–liquid oxidation processes for continuous synthesis of chemicals in a safe, efficient, and controlled manner. Herein, we discuss the key aspects of gas–liquid dispersion and hydrodynamics, as well as mass transfer characteristics on microscale, and present representative gas–liquid oxidation cases in microflow reactors. Finally, the current challenges in industrial applications and potential academic research directions are presented. 1 Introduction 2 Microbubble Generation Technology for Gas–Liquid Oxidation Reactions 3 Hydrodynamic and Mass-Transfer Characteristics of Gas–Liquid Oxidation Microreactors 4 Gas–Liquid Oxidation Reactions in Microreactors 5 Conclusion and Outlook