心肾综合症
医学
败血症
急性肾损伤
发病机制
多器官功能障碍综合征
器官功能障碍
重症监护医学
心脏功能不全
心脏病学
病因学
内科学
肾
心力衰竭
作者
Aditya Kotecha,Saraschandra Vallabhajosyula,Hongchuan Coville,Kianoush Kashani
标识
DOI:10.1016/j.jcrc.2017.08.044
摘要
Multi-organ dysfunction is seen in nearly 40–60% of all patients presenting with sepsis, including renal and cardiac dysfunction. Cardiorenal syndrome type-5 reflects concomitant cardiac and renal dysfunction secondary to a systemic condition that primarily affects both organs, such as sepsis. There are limited data on the etiology, pathogenesis and clinical implications of cardiorenal syndrome in sepsis. Cardiac dysfunction and injury can be measured with cardiac biomarkers, echocardiographic dysfunction, and hemodynamic parameters. Acute kidney injury is systematically evaluated using serum creatinine and urine output criteria. This review seeks to systematically describe the epidemiology, risk factors, pathogenesis, diagnosis and management of cardiorenal syndrome type-5 in the setting of sepsis.
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