牙龈卟啉单胞菌
微生物群
基因组
生物
厌氧菌
微生物学
生物信息学
细菌
遗传学
基因
作者
Charles-Antoine Guilloux,Claudie Lamoureux,Clémence Beauruelle,Geneviève Héry-Arnaud
出处
期刊:Anaerobe
[Elsevier]
日期:2021-04-01
卷期号:68: 102230-102230
被引量:20
标识
DOI:10.1016/j.anaerobe.2020.102230
摘要
Anaerobes form a large part of microbial communities, and have begun to be specifically studied in both healthy and pathologic contexts. Porphyromonas is one of the top ten anaerobic taxa in the microbiome (anaerobiome) in healthy subjects. However, to date, most studies focused on the deleterious role of P. gingivalis, the most widely described species. Interestingly, targeted metagenomics reveals Porphyromonas other than gingivalis (POTG), highlighting other species such as P. catoniae or P. pasteri as potential biomarkers in disease progression or pathogen colonization susceptibility. From the sparse data, it appears that the Porphyromonas genus may also be a relevant target of investigation in several pulmonary diseases. Moreover, deciphering cutaneous, gastric and oral microbiomes hint that Porphyromonas may be a genus of interest in non-pulmonary diseases. This review aims to summarize the major data on POTG and to report their impact on the various human microbiomes in different clinical states.
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