功能磁共振成像
神经科学
连接体
静息状态功能磁共振成像
人类连接体项目
空间组织
功能连接
职能组织
空间生态学
功能专门化
计算机科学
生物
进化生物学
生态学
作者
Taylor Bolt,Jason S. Nomi,Danilo Bzdok,Jorge A. Salas,Catie Chang,B.T. Thomas Yeo,Lucina Q. Uddin,Shella Keilholz
标识
DOI:10.1038/s41593-022-01118-1
摘要
Resting-state functional magnetic resonance imaging (MRI) has yielded seemingly disparate insights into large-scale organization of the human brain. The brain's large-scale organization can be divided into two broad categories: zero-lag representations of functional connectivity structure and time-lag representations of traveling wave or propagation structure. In this study, we sought to unify observed phenomena across these two categories in the form of three low-frequency spatiotemporal patterns composed of a mixture of standing and traveling wave dynamics. We showed that a range of empirical phenomena, including functional connectivity gradients, the task-positive/task-negative anti-correlation pattern, the global signal, time-lag propagation patterns, the quasiperiodic pattern and the functional connectome network structure, are manifestations of these three spatiotemporal patterns. These patterns account for much of the global spatial structure that underlies functional connectivity analyses and unifies phenomena in resting-state functional MRI previously thought distinct.
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