Cardiac diastolic dysfunction: basic and clinic researches

Cardiac diastolic dysfunction (CDD) means impaired relaxation and compliance decrease of the heart, resulting a filling dysfunction of left ventricle and even cardiac remodeling.However, the systolic functions are usually normal.At present, original articles of CDD are studied less, but epidemiological studies do showed that the incidence of CDD is common in the population, also, CDD showed strong correlation with all cause mortality.Without treatment, CDD may progress into diastolic heart failure, recently, as known as heart failure with preserved ejection fraction (HFpEF). Therefore, strengthen the understanding of CDD is significant in decreasing its incidence and improving CDD′s prognosis. Key words: Cardiac diastolic dysfunction; Heart failure with preserved ejection fraction; Cardiac troponin I; Ca2+