Comutation of PIK3CA and TP53 in Residual Disease After Preoperative Anti-HER2 Therapy in ERBB2 (HER2)-Amplified Early Breast Cancer
曲妥珠单抗
拉帕蒂尼
表阿霉素
医学
乳腺癌
肿瘤科
活检
癌症
内科学
病理
作者
Frankie A. Holmes,Maren K. Levin,Ying Cao,Sohail Balasubramanian,Jeffrey S. Ross,Lea Krekow,Kristi McIntyre,Cynthia R. Osborne,Virginia Espina,Lance A. Liotta,Joyce O’Shaughnessy
出处
期刊：JCO precision oncology [Lippincott Williams & Wilkins] 日期：2019-06-04卷期号：3 (3): 1-26被引量：4
HER2-amplified RD tissue after preoperative H, L, or H+L plus chemotherapy was enriched for PIK3CA and TP53 comutations, and the RD tissue demonstrated activation of EGFR/AKT/mTOR signaling on RPPA.
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(2025-6-4)
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