Downregulation of YAP in Clear Cell Renal Cell Carcinoma Contributes to Poor Prognosis and Progressive Features.

THE GOAL: To investigate the expression of Yes-associated protein (YAP) in clear cell renal cell carcinoma (ccRCC) and its clinical/prognostic significance. PROCEDURES: The expression of YAP protein was evaluated in tissue microarray by immunohistochemistry. Correlation between YAP expression and clinicopathological characteristics of renal cell carcinoma was analyzed. RESULTS: <0.05). CONCLUSIONS: Downregulation of YAP in clear cell renal cell carcinoma (ccRCC) may contribute to poor prognosis and progressive features.