Iterative C−H Functionalization Leading to Multiple Amidations of Anilides

Abstract Polyaminobenzenes were synthesized by the ruthenium‐catalyzed iterative C−H amidation of anilides using dioxazolones as an amino source. This strategy could be implemented by the sequential activation of C−H bonds of formerly generated compounds by cascade chelation assistance of newly installed amide groups. Computational studies provided a rationale.