Screening strategy of aptamer and its application in food contaminants determination

• This manuscript categorizes aptamer selection techniques and provides an updated compilation of aptamer sequences with high specificity for food contaminants. Furthermore, this manuscript also delved into the potential benefits of aptamers obtained through modified SELEX in mitigating matrix interference in food detection. • Description of the principles of the different SELEX techniques. • Aptamer sequences for different types of food contaminants are summaried. • An overview of the aptasensors for food contaminants. • The future directions of SELEX technology are discussed.