环加成
合成子
脱羧
化学
催化作用
钯
有机化学
药物化学
作者
Wei Xiong,Shengjun Zhang,Huijun Li,Zhifeng Zhang,Tongyu Xu
标识
DOI:10.1021/acs.joc.0c00243
摘要
An efficient route for formal [3 + 2] cycloaddition of vinylethylene carbonates with isothiocyanates was developed for the synthesis of 1,3-oxazolidine-2-thione derivatives. The zwitterionic π-allyl palladium intermediates formed in situ by decarboxylation of VECs acted as the three-membered synthons. In this transformation, the C-N bond formation was selectively realized over the C-S bond formation.
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