Visualization of Thromboinflammation by 18F-DPA-714 PET in a Stroke Patient

Abstract A 44-year-old man who presented with progressive right limb weakness was diagnosed with ischemic stroke. He was referred for 18 F-DPA-714 PET/CT for evaluation of the disease. 18 F-DPA-714 PET/CT showed increased uptake of the intracranial thrombus. This DPA-714–avid thrombus highly suggested the involvement of immune cells in the extension of the clot resulting in neurological deterioration. This present case suggested that 18 F-DPA-714 PET might be a promising tracer in visualizing thromboinflammation in vivo.