医学
创伤弧菌
抗生素
强力霉素
头孢菌素
内科学
重症监护医学
微生物学
细菌
遗传学
生物
作者
Na Ra Yun,Dong-Min Kim
出处
期刊:The Korean Journal of Internal Medicine
日期:2018-11-01
卷期号:33 (6): 1070-1078
被引量:43
标识
DOI:10.3904/kjim.2018.159
摘要
Vibrio vulnificus is a gram-negative bacterium that can cause serious, potentially fatal infections. V. vulnificus causes three distinct syndromes: an overwhelming primary septicemia caused by consuming contaminated seafood, wound infections acquired when an open wound is exposed to contaminated warm seawater, and gastrointestinal tract-limited infections. Case-fatality rates are higher than 50% for primary septicemia, and death typically occurs within 72 hours of hospitalization. Risk factors for V. vulnificus infection include chronic liver disease, alcoholism, and hematological disorders. When V. vulnificus infection is suspected, appropriate antibiotic treatment and surgical interventions should be performed immediately. Third-generation cephalosporin with doxycycline, or quinolone with or without third-generation cephalosporin, may be potential treatment options for patients with V. vulnificus infection.
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