医学
改良兰金量表
内科学
冲程(发动机)
巴氏指数
中性粒细胞与淋巴细胞比率
急性中风
接收机工作特性
伯格天平
多元分析
缺血性中风
生物标志物
物理疗法
淋巴细胞
平衡(能力)
日常生活活动
缺血
组织纤溶酶原激活剂
化学
工程类
机械工程
生物化学
作者
Min-Su Kim,Min Young Heo,Hyo Jin Joo,Ga Yang Shim,Jinmann Chon,Sung Joon Chung,Yunsoo Soh,Myung Chul Yoo
标识
DOI:10.3390/ijerph20020898
摘要
Background: Neutrophil-to-lymphocyte ratio (NLR), a systemic inflammatory biomarker, has been associated with poorer outcomes in acute ischemic stroke patients. The present study was designed to expand these findings by investigating the association between NLR and short-term functional outcomes in acute ischemic stroke patients. Methods: This retrospective study evaluated patients within 7 days after the onset of acute ischemic stroke. Stroke severity on admission was measured using the National Institutes of Health Stroke Scale (NIHSS). The functional outcomes were assessed using the Berg Balance Scale (BBS), Manual Function Test (MFT), the Korean version of the modified Barthel Index (K-MBI), and the Korean Mini-Mental State Examination (K-MMSE) within 2 weeks of stroke onset. The modified Rankin Scale (mRS) was evaluated at discharge. Results: This study included 201 patients, who were grouped into three NLR tertiles (<1.84, 1.84–2.71, and >2.71) on admission. A multivariate analysis showed that the top tertile group (NLR > 2.71) had significantly higher risks of unfavorable outcomes on the K-MBI (p = 0.010) and K-MMSE (p = 0.029) than the bottom tertile group (NLR < 1.84). Based on the optimal cut-off values from a receiver operating characteristic curve analysis, a higher NLR was significantly associated with higher NIHSS scores (p = 0.011) and unfavorable outcomes on the K-MBI (p = 0.002) and K-MMSE (p = 0.001). Conclusions: A higher NLR is associated with poorer short-term functional outcomes in acute ischemic stroke patients.
科研通智能强力驱动
Strongly Powered by AbleSci AI